Pathogenesis of Polymicrobial Biofilms

Pathogenesis of Polymicrobial Biofilms

In polymicrobial biofilms a high level of interspecies interactions occur with often detrimental effect to the host. Many chronic infections are attributed to polymicrobial biofilms which tend to exhibit increased resistance to antimicrobial therapy. Yet despite the gravity of such infections, areas of study in polymicrobial diseases are in their infancy. Thus, much work is needed to promote a ...

Fungal Biofilms and Polymicrobial Diseases

Biofilm formation is an important virulence factor for pathogenic fungi. Both yeasts and filamentous fungi can adhere to biotic and abiotic surfaces, developing into highly organized communities that are resistant to antimicrobials and environmental conditions. In recent years, new genera of fungi have been correlated with biofilm formation. However, Candida biofilms remain the most widely stud...

Diseases Associated with Oral Polymicrobial Biofilms

The human body can be defined as a symbiotic interaction between eukaryotic cells and prokaryotic cells. The body contains approximately ten times more microbial cells than mammalian cells. Fortunately, a large segment of the microbiome is both helpful and non-harmful, and constitutes the normal microbiome throughout the entire body. The digestive tract and the skin are the most microbial-rich ...

Recent Advances in Studies of Polymicrobial Interactions in Oral Biofilms

The oral cavity supports a complex and finely balanced consortia of microbial species, many of which co-operate within structured biofilms. These communities develop through multitudinous synergistic and antagonistic inter-species relationships. Changes in the dynamics of oral microbial populations are associated with the transition from healthy teeth and gums to dental caries, gingivitis and p...

Rapid Dispersion of Polymicrobial Wound Biofilms with Depolymerase Enzymes